abstract：INTRODUCTION:Funding for scientific advancement comes from two dominant sources: public funds used to generate knowledge, and private sector funds in the pursuit of commercial products. It is unclear how to compare the outputs of these two financial mechanisms because both sectors are motivated by common goods but are ...

journal_title：Expert review of medical devices

authors： Kang HD,Edelman ER,Ku DN

更新日期：2018-02-01 00:00:00

abstract：INTRODUCTION:The slow adoption of innovation into healthcare calls into question the manner of evidence generation for medical technology. This paper identifies potential reasons for this including a lack of attention to human factors, poor evaluation of economic benefits, lack of understanding of the existing healthca...

journal_title：Expert review of medical devices

authors： Borsci S,Uchegbu I,Buckle P,Ni Z,Walne S,Hanna GB

更新日期：2018-01-01 00:00:00

abstract：INTRODUCTION:the use of amplatzer occluder family in daily clinical practice has already overcome on-label indications, with growing clinical experience and the technological evolution of devices. Areas covered: We present the case of a patient with a very rare complication following proximal aortic surgery treated usi...

journal_title：Expert review of medical devices

authors： Toušek P,Kočka V,Petr R,Ulman J,Hlavička J,Kolesár M

更新日期：2017-11-01 00:00:00

abstract：INTRODUCTION:Despite the potential impact of missed visits on the outcomes of neuromodulation treatments, it is not clear how this issue has been addressed in clinical trials. Given this gap in the literature, we reviewed articles on non-invasive brain stimulation in participants with depression or chronic pain, and in...

journal_title：Expert review of medical devices

authors： Thibaut A,O'Brien AT,Fregni F

更新日期：2017-08-01 00:00:00

abstract：INTRODUCTION:Improved survival following single ventricle palliation has led to a large population of patients with a univentricular circulation, many of whom develop heart failure. Increasing experience with ventricular assist devices (VAD) in children has paved the way for VAD support in those with failing univentric...

journal_title：Expert review of medical devices

authors： Buratto E,Shi WY,Ye XT,Konstantinov IE

更新日期：2017-06-01 00:00:00

abstract：INTRODUCTION:Mechanical circulatory support (MCS) is an increasingly utilized mode of therapy in the management of advanced heart failure, both as bridge to heart transplantation and destination therapy. As MCS becomes more prevalent, it is ever more important to understand the complex hemodynamics of these devices, as...

journal_title：Expert review of medical devices

authors： Chung BB,Sayer G,Uriel N

更新日期：2017-05-01 00:00:00

abstract：INTRODUCTION:Transcatheter devices have contributed significantly to the advances achieved in treating many cardiovascular conditions over the last few decades. Sophisticated and detailed preclinical testing is not only a regulatory requirement to support an investigational device exemption (IDE) application, but more ...

journal_title：Expert review of medical devices

authors： Holzer R,Goble J,Hijazi Z

更新日期：2017-02-01 00:00:00

abstract：INTRODUCTION:Anastomotic leak (AL) after colorectal surgery is a devastating complication; decreased blood perfusion is an important risk factor. Surgeons rely on subjective measures to assess bowel perfusion. Fluorescence imaging (FI) with indocyanine green (ICG) provides a real-time objective assessment of intestinal...

journal_title：Expert review of medical devices

authors： Mizrahi I,Wexner SD

更新日期：2017-01-01 00:00:00

abstract：INTRODUCTION:Percutaneous transcatheter balloon angioplasty has evolved to the current mainstay treatment for salvage of dysfunctional dialysis access. Nonetheless, it is frequently associated with recurrent vessel restenosis and the need for multiple repeat treatments in order to maintain hemodynamic patency. Cutting-...

journal_title：Expert review of medical devices

authors： Kitrou P,Spiliopoulos S,Karnabatidis D,Katsanos K

更新日期：2016-12-01 00:00:00

abstract：INTRODUCTION:Refinements in endovascular technology have revolutionized the treatment of intracranial aneurysms (IAs) with the development of flow-diversion technology. The first generation of the Pipelin Embolization Device (PED) has demonstrated its safety and efficacy. However, the deployment technique was a difficu...

journal_title：Expert review of medical devices

authors： Aguilar-Salinas P,Brasiliense LB,Gonsales D,Mitchell B,Lima A,Sauvageau E,Hanel R

更新日期：2016-10-01 00:00:00

abstract：INTRODUCTION:The surgical template is a guide aimed at directing the implant placement, tumor resection, osteotomy and bone repositioning. Using it, preoperative planning can be transferred to the actual surgical site, and the precision, safety and reliability of the surgery can be improved. However, the actual workflo...

journal_title：Expert review of medical devices

authors： Chen X,Xu L,Wang W,Li X,Sun Y,Politis C

更新日期：2016-09-01 00:00:00

abstract：INTRODUCTION:The present review aims to provide an overview of the most common uses of wearable inertial sensors in the field of clinical human movement analysis. AREAS COVERED:Six main areas of application are analysed: gait analysis, stabilometry, instrumented clinical tests, upper body mobility assessment, daily-li...

journal_title：Expert review of medical devices

authors： Iosa M,Picerno P,Paolucci S,Morone G

更新日期：2016-07-01 00:00:00

abstract：:Ventricular assist devices (VAD) are used for mechanical support of the terminally failing heart. Failure of these life supporting systems can be fatal. Early and reliable detection of any upcoming problems is mandatory and is crucial for the outcome. Medical imaging methods are described within this review, which are...

journal_title：Expert review of medical devices

authors： Kaufmann F,Krabatsch T

更新日期：2016-05-01 00:00:00

abstract：:Consumer sleep tracking devices such as fitness trackers and smartphone apps have become increasingly popular. These devices claim to measure the sleep duration of their users and in some cases purport to measure sleep quality and awaken users from light sleep, potentially improving overall sleep. Most of these device...

journal_title：Expert review of medical devices

authors： Kolla BP,Mansukhani S,Mansukhani MP

更新日期：2016-05-01 00:00:00

abstract：:Patients with primary and secondary liver cancers generally have a poor prognosis with limited potentially curative options. Liver-directed, intra-arterial therapies such as selective internal radiotherapy (SIRT) and trans-arterial chemoembolization (TACE) are taking a larger role in the management of these patients. ...

journal_title：Expert review of medical devices

authors： Kim AY,Miller A

更新日期：2016-05-01 00:00:00

abstract：:APDM's Mobility Lab system provides portable, validated, reliable, objective measures of balance and gait that are sensitive to Parkinson's disease (PD). In this review, we describe the potential of objective measures collected with the Mobility Lab system for tracking longitudinal progression of PD. Balance and gait ...

journal_title：Expert review of medical devices

authors： Mancini M,Horak FB

更新日期：2016-05-01 00:00:00

abstract：:In the last 30 years, development of minimally invasive percutaneous procedures to treat cardiovascular defects has been thriving. Although these techniques present obvious advantages, like avoiding cardiopulmonary bypass, the passage of catheter systems and the deployment of devices in the blood circulation can cause...

journal_title：Expert review of medical devices

authors： Egron S,Kütting M,Marzelle J,Becquemin JP,Schmitz-Rode T,Steinseifer U

更新日期：2016-01-01 00:00:00

abstract：:In the last decade, bicomponent fibers have been proposed to fabricate bio-inspired systems for tissue repair, regenerative medicine, medical healthcare and clinical applications. In comparison with monocomponent fibers, key advantage concerns their ability of self-adapting to the physiological conditions through an e...

journal_title：Expert review of medical devices

authors： Guarino V,Cirillo V,Ambrosio L

更新日期：2016-01-01 00:00:00

abstract：:Over the last decade, the use of electrosurgical devices has become commonplace across all surgical specialities. The current market is large enough to warrant a comparative review of each device. This has even more impetus given the budgetary constraints of NHS organisations. This review aims to compare the benefits ...

journal_title：Expert review of medical devices

authors： Sran H,Sebastian J,Hossain MA

更新日期：2016-01-01 00:00:00

abstract：:Precise and accurate biomechanical reconstruction during total hip arthroplasty (THA) is essential for durable long-term survivorship. Accurate fit of cementless hip implants is also crucial to reduce micromotion between the bone-implant interfaces to allow for stable osseointegration. Robotic technology aims to minim...

journal_title：Expert review of medical devices

authors： Banerjee S,Cherian JJ,Elmallah RK,Pierce TP,Jauregui JJ,Mont MA

更新日期：2016-01-01 00:00:00

abstract：:Acute ischemic stroke is caused by occlusion of a cerebral artery, resulting in loss of brain tissue and neurologic deficits. However, a portion of the ischemic brain can be salvaged if blood flow is restored within an appropriate time frame. The past year has seen the publication of five positive randomized controlle...

journal_title：Expert review of medical devices

authors： Wallace AN,Kansagra AP,McEachern J,Moran CJ,Cross DT 3rd,Derdeyn CP

更新日期：2016-01-01 00:00:00

abstract：:Drug eluting stents and particularly the fully bioresorbable drug-eluting scaffolds herald a new era in percutaneous treatment of coronary artery disease. There has been tremendous progress in drug eluting stents with fully biodegradable coating polymers and polymer-free devices with reservoir technology planting the ...

journal_title：Expert review of medical devices

authors： Tenekecioglu E,Bourantas C,Abdelghani M,Zeng Y,Silva RC,Tateishi H,Sotomi Y,Onuma Y,Yılmaz M,Serruys PW

更新日期：2016-01-01 00:00:00

abstract：:Liver biology, liver disease and its management present a myriad of challenges to clinicians. Difficulties arise in determining liver functional capacity, which must be effectively measured in a quantitative reproducible manner. Measurement of indocyanine green (ICG) clearance, an exceptional tool that has been used f...

journal_title：Expert review of medical devices

authors： Mobley CM,Zarrinpar A

更新日期：2016-01-01 00:00:00

abstract：:The evidence on digital breast tomosynthesis (DBT), or quasi-3D-mammography, for population breast screening has emerged rapidly: two prospective and several retrospective studies provide convincing evidence that mammography with DBT improves screening detection measures compared with standard mammography. Based on po...

journal_title：Expert review of medical devices

authors： Houssami N

更新日期：2015-07-01 00:00:00

abstract：:Temperature analysis has been considered as a complementary method in medical evaluation and diagnosis. Several studies demonstrated that monitoring the temperature variations of the feet of diabetic patients can be helpful in the early identification of diabetic foot manifestations, and also in changing behaviors, wh...

journal_title：Expert review of medical devices

authors： Sousa P,Felizardo V,Oliveira D,Couto R,Garcia NM

更新日期：2015-07-01 00:00:00

abstract：:A wearable and, ultimately, an implantable artificial kidney is a long-held aim in the treatment of patients with end-stage renal disease, provided that it would combine continuous blood purification, preventing the fluctuations in the internal environment associated with hemodialysis, while maintaining a high efficie...

journal_title：Expert review of medical devices

authors： Kooman JP,Joles JA,Gerritsen KG

更新日期：2015-07-01 00:00:00

abstract：:Minimally invasive, catheter-based treatment of valvular dysfunction has become an integral part of clinical routine. As left heart valvular disease is much more common and thus commercially of interest, transcatheter solutions for the treatment of aortic and mitral valvular defects were the first to become broadly cl...

journal_title：Expert review of medical devices

authors： Kuetting M,Pott D,Sedaghat A,Ng YA,Egron S,Rosefort C,Werner N,Sachweh J,Steinseifer U

更新日期：2015-03-01 00:00:00

abstract：:Diabetic retinopathy (DR) is a common complication of diabetes. DR obstructs blood supply to the retina and has serious and long-lasting detrimental effects on quality of life. Panretinal photocoagulation, a laser surgical intervention, is advocated for early treatment of DR to prevent visual loss; however, results fr...

journal_title：Expert review of medical devices

authors： Luo D,Zheng Z,Xu X,Fan Y,Zhu B,Liu K,Wang F,Sun X,Zou H,Xia X

更新日期：2015-01-01 00:00:00

abstract：:Insertable cardiac monitors (ICMs) are leadless subcutaneous devices that continuously monitor the heart rhythm and record events over a timeframe measured in years, allowing for the diagnosis of infrequent rhythm abnormalities that can be the cause of palpitations, syncope and stroke. To date, ICMs have primarily bee...

journal_title：Expert review of medical devices

authors： Tomson TT,Passman R

更新日期：2015-01-01 00:00:00

abstract：:Clinical applications in the developing world, such as malaria and anemia diagnosis, demand a change in the medical paradigm of expensive care given in central locations by highly trained professionals. There has been a recent explosion in optical technologies entering the consumer market through the widespread adopti...

journal_title：Expert review of medical devices

authors： Chu K,Smith ZJ,Wachsmann-Hogiu S

更新日期：2015-01-01 00:00:00

abstract：:The discrepancy between the number of patients on the waiting list and available donor hearts has led to the successful development of left ventricular assist devices (LVAD) as a bridge to transplantation. The conventional LVADs are designed to provide full hemodynamic support for the end-stage failing heart. However,...

journal_title：Expert review of medical devices

authors： Mohite PN,Sabashnikov A,Simon AR,Weymann A,Patil NP,Unsoeld B,Bireta C,Popov AF

更新日期：2015-01-01 00:00:00

abstract：:Considerable research efforts have recently been dedicated to the establishment of various drug delivery systems (DDS) that are mechanical/physical, chemical and biological/molecular DDS. In this paper, we report on the recent advances in site-specific drug delivery (site-specific, controlled, targeted or smart drug d...

journal_title：Expert review of medical devices

authors： Alici G

更新日期：2015-01-01 00:00:00

abstract：:Mechanical circulatory support devices are the mainstay of treatment for severe cardiogenic shock refractory to pharmacologic therapy. Their evolution over the past few decades has been remarkable with a common theme of developing reliable, less bulky and more easily percutaneously implantable devices. The goal of thi...

journal_title：Expert review of medical devices

authors： Koprivanac M,Kelava M,Soltesz E,Smedira N,Kapadia S,Brzezinski A,Alansari S,Moazami N

更新日期：2015-01-01 00:00:00

abstract：:Transcatheter aortic valve implantation (TAVI) is a widely used intervention in patients who are at high risk or contraindicated for cardiac surgery. The procedure is technically feasible in most patients and has very good mid-term clinical outcomes. In this special report, we evaluated the long-term outcome after TAV...

journal_title：Expert review of medical devices

authors： Sulzenko J,Tousek P,Kocka V,Widimsky P

更新日期：2015-01-01 00:00:00

abstract：:The RNS(®) System is the first commercially available device to provide closed-loop responsive brain stimulation. The system includes a cranially implanted neurostimulator that continually monitors the electrocorticogram through one or two depth and/or subdural cortical strip leads that are placed at the seizure focus...

journal_title：Expert review of medical devices

authors： Sun FT,Morrell MJ

更新日期：2014-11-01 00:00:00

abstract：:Left atrial appendage device occlusion for the preventions of systemic thromboembolism and stroke represents a major breakthrough in the field of cardiovascular disease. The wide prevalence of atrial fibrillation with devastating consequences of thromboembolic stroke as a result of thrombus arising from the left atria...

journal_title：Expert review of medical devices

authors： Alli O,Holmes D Jr

更新日期：2014-11-01 00:00:00

abstract：:Methotrexate (MTX) is the cornerstone of treatment for rheumatoid arthritis (RA), and is widely used both as first-line therapy and as an important component of long-term therapy. Although subcutaneous MTX is typically delivered orally, parenteral administration offers benefits with respect to tolerability and systemi...

journal_title：Expert review of medical devices

authors： Schiff M,Jaffe J,Freundlich B,Madsen P

更新日期：2014-09-01 00:00:00

abstract：:Robotic systems allow for mapping and ablation of different arrhythmia substrates replacing hand maneuvering of intracardiac catheters with machine steering. Currently there are four commercially available robotic systems. Niobe magnetic navigation system (Stereotaxis Inc., St Louis, MO) and Sensei robotic navigation ...

journal_title：Expert review of medical devices

authors： Shurrab M,Schilling R,Gang E,Khan EM,Crystal E

更新日期：2014-07-01 00:00:00

abstract：:Cardiac resynchronization therapy (CRT) is a proven treatment adjunct for selected patients with heart failure and evidence of ventricular dyssynchrony. When applying most contemporary guidelines the accepted response rate has remained static with up to one-third of patients failing to respond. Empiric lateral/postero...

journal_title：Expert review of medical devices

authors： Sohal M,Chen Z,Sammut E,Jackson T,Behar J,Carr-White G,Razavi R,Rinaldi CA

更新日期：2014-05-01 00:00:00

abstract：:Neurodegeneration in Parkinson's disease (PD) affects both the fine motor control of the fingers and gross movement of the upper limb. Handwriting examinations are commonly performed in the analysis of tremor in PD and there is validity in subjective assessment in the clinic. However, there is clinical need for a more...

journal_title：Expert review of medical devices

authors： Walker RW,Zietsma R,Gray WK

更新日期：2014-05-01 00:00:00